Abstract
Strategic cooperation between clinical research institutions engaged in medical research and pharmaceutical companies focused on identifying and testing targets aimed at creating new innovative, high-quality, safe, effective and affordable medicines to address the therapeutic needs of patients suffering from psychoneurological and related health disorders (multiple sclerosis, neuro-oncology, post-traumatic stress disorder, stroke, drug addiction, alcoholism, etc.) in accordance with the state guarantee program and ICD-11. At the same time, the relevance of the impact of non-drug methods on neuroplasticity in the neurorehabilitation system of patients is beyond doubt. The authors addressed the impact of non-drug methods on neuroplasticity in the neurorehabilitation system. Multilevel neuroplastic effects of electromagnetic fields caused by transcranial magnetic stimulation are presented. The effects of transcranial magnetic stimulation on neurotransmitters and synaptic plasticity, glial cells and the prevention of neuronal death are examined. The neurotrophic effects of transcranial magnetic stimulation on the growth of dendrites, growth and neurotrophic factors are described. The effect of transcranial magnetic stimulation on the genetic apparatus of neurons is traced. It has been demonstrated that transcranial magnetic stimulation has a proven ability to modulate the internal activity of the brain in a frequency-dependent manner, generate contralateral responses, provide, along with the neuromodulatory and neurostimulating effect, influence the brain as a global dynamic system.
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Copyright (c) 2025 Maksym Chernenko (Translator); Tetiana Nehreba, Nataliya Voloshyna, Vitaliy Vasylovskyy, Tetiana Pohulaieva, Ivan Voloshyn-Haponov Voloshyn-Haponov (Author)